:root{
  --bg: #EEF4F6;
  --bg-alt: #E4EDF0;
  --surface: #FFFFFF;
  --primary: #0F3D54;
  --primary-mid: #217491;
  --accent: #4FB6AC;
  --accent-strong: #2E9C90;
  --warn: #A63446;
  --warn-bg: #FBEAEC;
  --text: #12242C;
  --text-muted: #5B7480;
  --border: #DCE7EA;
  --radius-lg: 18px;
  --radius-md: 12px;
  --shadow: 0 1px 2px rgba(15,61,84,.06), 0 8px 24px -12px rgba(15,61,84,.18);
  --font-ui: 'IBM Plex Sans', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
  --font-mono: 'IBM Plex Mono', ui-monospace, SFMono-Regular, Menlo, monospace;
}

*{ box-sizing: border-box; }

html,body{
  margin:0;
  padding:0;
  background: var(--bg);
  color: var(--text);
  font-family: var(--font-ui);
  -webkit-font-smoothing: antialiased;
  min-height: 100dvh;
}

body{
  background:
    radial-gradient(1200px 600px at 100% -10%, rgba(33,116,145,.10), transparent 60%),
    radial-gradient(900px 500px at -10% 110%, rgba(79,182,172,.12), transparent 55%),
    var(--bg);
}

.hidden{ display:none !important; }

.app{
  max-width: 480px;
  margin: 0 auto;
  padding: max(16px, env(safe-area-inset-top)) 16px calc(32px + env(safe-area-inset-bottom));
  min-height: 100dvh;
  display:flex;
  flex-direction:column;
  gap: 14px;
}

/* Header */
.app-header{
  display:flex;
  align-items:center;
  justify-content:space-between;
  padding: 4px 2px 8px;
}
.brand{ display:flex; align-items:center; gap:12px; }
.brand-mark{ flex:none; line-height:0; filter: drop-shadow(0 4px 10px rgba(15,61,84,.25)); }
.brand-text h1{
  margin:0;
  font-size: 20px;
  font-weight: 700;
  letter-spacing: -0.01em;
  color: var(--primary);
}
.brand-text p{
  margin: 2px 0 0;
  font-size: 12.5px;
  color: var(--text-muted);
}
.icon-btn{
  border:none;
  background: var(--surface);
  color: var(--primary-mid);
  width: 38px; height:38px;
  border-radius: 999px;
  display:flex; align-items:center; justify-content:center;
  box-shadow: var(--shadow);
  cursor:pointer;
}
.icon-btn:active{ transform: scale(0.94); }

/* Cards */
main{ display:flex; flex-direction:column; gap: 14px; }

.card{
  background: var(--surface);
  border-radius: var(--radius-lg);
  padding: 16px 16px 18px;
  box-shadow: var(--shadow);
  border: 1px solid rgba(15,61,84,.04);
}

.card-title{
  margin: 0 0 12px;
  font-size: 13px;
  font-weight: 600;
  text-transform: none;
  color: var(--primary);
  display:flex;
  align-items:center;
  gap: 7px;
  letter-spacing: 0.01em;
}
.card-title .ic{ color: var(--accent-strong); flex:none; }

/* Drug select */
.select-wrap{
  position: relative;
  display:flex;
  align-items:center;
  min-height: 46px;
  background: var(--bg-alt);
  border: 1.5px solid var(--border);
  border-radius: var(--radius-md);
  padding: 0 40px 0 12px;
  transition: border-color .15s ease, background .15s ease;
}
.select-wrap:focus-within{
  border-color: var(--accent-strong);
  background: var(--surface);
}
.select-dot{
  width: 10px; height:10px; border-radius:50%;
  background: var(--dot, var(--primary-mid));
  flex: none;
  margin-right: 10px;
  pointer-events: none;
  position: relative;
  z-index: 1;
}
.select-wrap select{
  position: absolute;
  inset: 0;
  width: 100%;
  height: 100%;
  z-index: 2;
  border:none;
  background: transparent;
  appearance: none;
  -webkit-appearance: none;
  font-family: var(--font-ui);
  font-size: 15.5px;
  font-weight: 600;
  color: var(--text);
  padding: 0 40px 0 32px;
  outline:none;
  cursor: pointer;
}
.select-caret{
  position: absolute;
  right: 12px;
  top: 50%;
  transform: translateY(-50%);
  color: var(--text-muted);
  pointer-events:none;
  z-index: 1;
}

/* Fields */
.field-grid{
  display:flex;
  gap: 16px;
}
.field{ display:flex; flex-direction:column; gap:6px; flex: none; }
.field-label{
  font-size: 12.5px;
  color: var(--text-muted);
  font-weight: 500;
}
.field-input{
  width: 112px;
  display:flex;
  align-items:center;
  background: var(--bg-alt);
  border: 1.5px solid var(--border);
  border-radius: var(--radius-md);
  padding: 0 10px;
  transition: border-color .15s ease, background .15s ease;
}
.field-input:focus-within{
  border-color: var(--accent-strong);
  background: var(--surface);
}
.field-input input{
  flex:1;
  min-width:0;
  width: 100%;
  border:none;
  background: transparent;
  font-family: var(--font-mono);
  font-size: 15.5px;
  font-weight: 500;
  color: var(--text);
  padding: 11px 2px;
  outline:none;
}
.field-input input::placeholder{ color: #A9BCC3; }

/* quitar flechas nativas del input number (evita que el cuadro se desborde) */
.field-input input::-webkit-outer-spin-button,
.field-input input::-webkit-inner-spin-button{
  -webkit-appearance: none;
  margin: 0;
}
.field-input input[type="number"]{
  -moz-appearance: textfield;
  appearance: textfield;
}
.field-suffix{
  font-size: 12.5px;
  color: var(--text-muted);
  font-weight: 500;
}

/* Result card */
.result-card{
  background: linear-gradient(180deg, var(--surface), #FBFDFE);
}
.result-empty{
  font-size: 13.5px;
  color: var(--text-muted);
  padding: 6px 2px 2px;
}
.result-body{
  display:flex;
  flex-direction:column;
  gap: 12px;
}
.result-block{
  display:flex;
  flex-direction:column;
  gap: 3px;
  padding: 10px 12px;
  background: var(--bg-alt);
  border-radius: var(--radius-md);
}
.result-label{
  font-size: 11.5px;
  color: var(--text-muted);
  font-weight: 500;
}
.result-value{
  font-size: 14.5px;
  font-weight: 600;
  color: var(--text);
  line-height: 1.35;
}
.result-value.mono{ font-family: var(--font-mono); font-size: 14px; }

.result-block.warn{
  flex-direction: row;
  align-items: center;
  gap: 8px;
  background: var(--warn-bg);
  color: var(--warn);
  font-size: 12.5px;
  font-weight: 500;
}
.result-block.warn .ic{ flex:none; }

.result-highlight{
  display:flex;
  flex-direction:column;
  gap: 4px;
  padding: 16px 14px;
  border-radius: var(--radius-md);
  background: linear-gradient(135deg, var(--primary), var(--primary-mid));
  color: #fff;
  transition: filter .5s ease;
}
.result-highlight.pulse{ filter: brightness(1.18); }
.result-highlight .result-label{ color: rgba(255,255,255,.78); }
.result-big{
  font-size: 26px;
  font-weight: 600;
  letter-spacing: -0.01em;
}

.result-ref{
  display:flex;
  align-items:center;
  gap: 7px;
  font-size: 12px;
  color: var(--text-muted);
  padding: 0 2px;
}
.result-ref .ic{ flex:none; color: var(--accent-strong); }

.disclaimer{
  font-size: 11.5px;
  line-height: 1.5;
  color: var(--text-muted);
  text-align: center;
  padding: 4px 8px 0;
}
.disclaimer a{ color: var(--primary-mid); }

/* Modal */
.modal-backdrop{
  position: fixed;
  inset: 0;
  background: rgba(15,36,44,.45);
  display:flex;
  align-items:flex-end;
  justify-content:center;
  z-index: 50;
  padding: 16px;
}
@media (min-width: 520px){
  .modal-backdrop{ align-items:center; }
}
.modal{
  background: var(--surface);
  border-radius: var(--radius-lg);
  padding: 20px;
  max-width: 420px;
  width:100%;
  box-shadow: 0 20px 60px rgba(0,0,0,.25);
}
.modal h3{ margin:0 0 10px; color: var(--primary); font-size:16px; }
.modal p{ margin: 0 0 10px; font-size: 13.5px; line-height:1.5; color: var(--text); }
.btn-primary{
  margin-top: 8px;
  width:100%;
  border:none;
  background: var(--primary);
  color:#fff;
  font-family: var(--font-ui);
  font-weight: 600;
  font-size: 14px;
  padding: 12px;
  border-radius: var(--radius-md);
  cursor:pointer;
}
.btn-primary:active{ transform: scale(0.98); }

@media (prefers-reduced-motion: reduce){
  .result-highlight{ transition:none; }
}